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Regulation of the immune system by SOCS family adaptor proteins

✍ Scribed by Subburaj Ilangumaran; Sheela Ramanathan; Robert Rottapel

Book ID
116885372
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
371 KB
Volume
16
Category
Article
ISSN
1044-5323

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## Abstract Ubiquitination is essential in mediating diverse cellular functions including protein degradation and trafficking. Ubiquitin‐protein (E3) ligases determine the substrate specificity of the ubiquitination process. The Nedd4 family of E3 ligases is an evolutionarily conserved family of pr