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Regulation of the FoxO family of transcription factors by phosphatidylinositol-3 kinase-activated signaling

โœ Scribed by Karen C Arden; William H Biggs III

Book ID
117042079
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
219 KB
Volume
403
Category
Article
ISSN
0003-9861

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## Background Phosphatidylinositol (PI) 3-kinase is activated by a variety of growth factor receptors and the PI 3-kinase/Akt signaling pathway is a key regulator of cell proliferation and survival. The downstream targets of PI 3-kinase/Akt signaling include direct regulators of cell cycle progress