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Regulation of the Chemokine System at the Level of Chemokine Receptor Expression and Signaling Activity

✍ Scribed by Massimo Locati; Elena Riboldi; Karel Otero; Fernando O. Martinez; Federica Riva; Patrick Perrier; Stefania Baviera; Paola Signorelli; Raffaella Bonecchi; Paola Allavena; Silvano Sozzani; Alberto Mantovani

Book ID
117850800
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
47 KB
Volume
204
Category
Article
ISSN
0171-2985

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## Abstract ## Objective Rheumatoid arthritis (RA) is a chronic inflammatory condition characterized by a cellular influx and destruction of the joint architecture. Chemokines characteristically regulate leukocyte recruitment and activation. Chemokine (CC motif) receptor–like 2 (CCRL2) is an orpha