Characterization of a tumorigenic murine
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Varda Mann; Moshe Szyf; Aharon Razin; Evelyne Chriqui-Zeira; Eli Kedar
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Article
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1986
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John Wiley and Sons
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French
⚖ 593 KB
The establishment of IL-2-independent T-cell lines spontaneously derived from long-term IL-2-dependent cytotoxic T-cell lines is described. Two lines (cloned and uncloned) studied in detail have shown the following characteristics: (1) Permanent loss of IL-2 dependence. (2) Partial or complete loss