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Regulation of T cell-dependent autoantibody production by a γδ T cell line derived from lupus-prone mice

✍ Scribed by Takao Fujii; Masato Okada; Joe Craft


Book ID
114008155
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
652 KB
Volume
217
Category
Article
ISSN
0008-8749

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The establishment of IL-2-independent T-cell lines spontaneously derived from long-term IL-2-dependent cytotoxic T-cell lines is described. Two lines (cloned and uncloned) studied in detail have shown the following characteristics: (1) Permanent loss of IL-2 dependence. (2) Partial or complete loss