𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Regulation of Sterol Synthesis in Eukaryotes

✍ Scribed by Espenshade, Peter J.; Hughes, Adam L.


Book ID
111679041
Publisher
Annual Reviews
Year
2007
Tongue
English
Weight
489 KB
Volume
41
Category
Article
ISSN
0066-4197

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✍ A. A. Kandutsch; H. W. Chen πŸ“‚ Article πŸ“… 1975 πŸ› John Wiley and Sons 🌐 English βš– 672 KB

Sterol synthesis in liver in vivo is regulated at the site of the reaction catalyzed by 3-hydroxy-3-methylglutaryl-CoA reductase through a feedback system thought to involve either cholesterol or one or more of the products of its metabolism. Cholesterol feeding results in repression of the synthesi