Hybrids were isolated between rat glial cells and mouse fibroblasts. Micro complement (C') fixation was used to assay S100, a highly acidic protein specific for nervous tissues, The glial cells contain large amounts of S100. Extracts of the fibroblasts contain some C' fixing material which is detect
Regulation of Specific Functions of Glial Cells in Somatic Hybrids, II. Control of Inducibility of Glycerol-3-Phosphate Dehydrogenase
β Scribed by Richard L. Davidson and Philippe Benda
- Book ID
- 123650147
- Publisher
- National Academy of Sciences
- Year
- 1970
- Tongue
- English
- Weight
- 262 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/60583
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Our previous studies using rodent/human somatic-cell hybrids suggested that the expression of human mitochondrial glycerol-3-phosphate dehydrogenase (GPDM) is dependent on the presence of human mitochondria. This has now been tested directly by analysis of GPDM activity in a series of nine hybrid-ce
Increases in the mRNA levels of two neuroglial markers, glutamine synthetase (EC 6.3.1.2; GS) and glycerolphosphate dehydrogenase (EC 1.1.1.8; GPDH), were observed in hydrocortisone-treated cultures of astrocytes and oligodendrocytes, respectively, and in C6 cells by Northern blot analysis and in si