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Regulation of secretory type-II phospholipase A2 and of lysophosphatidic acid synthesis

✍ Scribed by Olivier Fourcade; FranÇois Le Balle; Josette Fauvel; Marie-FranÇoise Simon; Hugues Chap

Book ID
117259386
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
181 KB
Volume
38
Category
Article
ISSN
0065-2571

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✍ K Koumanov; A Momchilova; C Wolf 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 177 KB

Melittin and phospholipase A 2 -activating protein (PLAP) are known as efficient activators of secretory phospholipase A 2 (sPLA 2 ) types I, II, and III when phospholipid liposomes are used as substrate. The present study demonstrates that both peptides can either inhibit or activate sPLA 2 dependi