Reversible translocation of p115-RhoGEF
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Bruno H. Meyer; Felix Freuler; Danilo Guerini; Sandra Siehler
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Article
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2008
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John Wiley and Sons
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English
β 242 KB
## Abstract G proteinβcoupled receptors (GPCRs) are important targets for medicinal agents. Four different G protein families, G~s~, G~i~, G~q~, and G~12~, engage in their linkage to activation of receptorβspecific signal transduction pathways. G~12~ proteins were more recently studied, and upon ac