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Regulation of renin secretion by renal juxtaglomerular cells

✍ Scribed by Friis, Ulla G.; Madsen, Kirsten; Stubbe, Jane; Hansen, Pernille B. L.; Svenningsen, Per; Bie, Peter; Skøtt, Ole; Jensen, Boye L.

Book ID
120526119
Publisher
Springer
Year
2012
Tongue
English
Weight
362 KB
Volume
465
Category
Article
ISSN
0031-6768

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Amiloride enhances the secretion but not
Amiloride enhances the secretion but not the synthesis of renin in renal juxtaglomerular cells
✍ Armin Kurtz; Roberto Bruna; Holger Scholz; Wolfgang Baier 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 670 KB

In this study we have examined a potential role of the sodium/proton exchange system in the regulation of renin secretion. We found that the inhibitors of the Na+/H + antiport, amiloride (1 mM) and ethylisopropylamiloride (EIPA, 50 ~tM), led to a 125% increase of renin secretion from cultured mouse