✦ LIBER ✦

Regulation of RAG expression in developing lymphocytes

✍ Scribed by Hitoshi Nagaoka; Wong Yu; Michel C Nussenzweig

Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 80 KB
Volume: 12
Category: Article
ISSN: 0952-7915
DOI: 10.1016/s0952-7915(99)00070-9

No coin nor oath required. For personal study only.

✦ Synopsis

Proper expression of products of the recombination-activating genes (RAGs) is essential for the development of the adaptive immune system. A major advance in the past year toward understanding RAG regulation is the establishment of green fluorescent protein (GFP)-RAG indicator mouse strains. In vivo visualization of RAG expression in single cells has helped to define the cells that express RAGs in secondary lymphoid organs and revealed differential cis requirements for stage-and lineage-specific RAG expression.

📜 SIMILAR VOLUMES

Regulation of expression of transgenes i

Regulation of expression of transgenes in developing fish

✍ Boaz Moav; Zhanjiang Liu; Ljubica D. Caldovic; Mark L. Gross; Anthony J. Faras; 📂 Article 📅 1993 🏛 Springer Netherlands 🌐 English ⚖ 927 KB

Re-expression of RAG-1 and RAG-2 genes a

Re-expression of RAG-1 and RAG-2 genes and evidence for secondary rearrangements in human germinal center B lymphocytes

✍ Claudia Giachino; Elisabetta Padovan; Antonio Lanzavecchia 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 186 KB

Spatial regulation of floating head expr

Spatial regulation of floating head expression in the developing notochord

✍ Anna E. Melby; David Kimelman; Charles B. Kimmel 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 240 KB 👁 2 views

The zebrafish homeobox gene floating head ( flh) is essential for notochord development and is one of the earliest genes to be expressed in notochord precursors. To understand how flh is regulated during notochord development, we compared the wild-type flh expression pattern to that in embryos mutan

Regulation of the expression of lactate

Regulation of the expression of lactate dehydrogenase isozymes in human lymphocytes

✍ Patrik Wollberg; B. Dean Nelson 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 624 KB

Regulation of RAG-1 and CD69 expression

Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection

✍ Daniel Brändle; Stefan Müller; Christoph Müller; Hans Hengartner; Hanspeter Pirc 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 823 KB

Regulation of adenosine receptors expres

Regulation of adenosine receptors expression in rat B lymphocytes by insulin

✍ Monika Sakowicz-Burkiewicz; Katarzyna Kocbuch; Marzena Grden; Andrzej Szutowicz; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 326 KB

## Abstract Development of diabetes is associated with altered expression of adenosine receptors (ARs). Some of these alterations might be attributed to changes in insulin concentration. This study was undertaken to investigate the possible insulin effect on ARs level, and to determine the signalin