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Regulation of pyrimidine nucleotide synthesis by growth factor-stimulated phosphorylation

โœ Scribed by L.M. Graves

Book ID
117575182
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
204 KB
Volume
54
Category
Article
ISSN
0753-3322

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The receptor for epidermal growth factor (EGF) is a glycosylated transmembrane phosphoprotein that exhibits EGF-stimulable protein tyrosine kinase activity. On EGF stimulation, the receptor undergoes a self-phosphorylation reaction at tyrosine residues located primarily in the extreme carboxyl-termi