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Regulation of proximal tubular epithelial cell CD44-mediated binding and internalisation of hyaluronan

✍ Scribed by Stuart George Jones; Takafumi Ito; Aled Owain Phillips

Book ID
117756045
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
606 KB
Volume
35
Category
Article
ISSN
1357-2725

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## Abstract ## Aim It was the aim of this study to prepare purified DNA/PEI polyplexes, which are coated with hyaluronan to facilitate CD44 receptor mediated uptake of the DNA/PEI polyplex and to reduce unspecific interactions of the complex with negatively charged extracellular matrix components