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Regulation of Prostatic Acid Phosphatase Expression and Secretion by Androgen in LNCaP Human Prostate Carcinoma Cells

โœ Scribed by M.F. Lin; R. Garciaarenas; Y.C. Chao; M.M.C. Lai; P.C. Patel; X.Z. Xia


Book ID
115564255
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
716 KB
Volume
300
Category
Article
ISSN
0003-9861

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## Abstract Activation of PKCฮด in androgenโ€dependent LNCaP prostate cancer cells leads to apoptosis via the activation of p38 MAPK and JNK cascades. We have recently shown that treatment of LNCaP cells with phorbol 12โ€myristate 13โ€acetate (PMA) leads to a PKCฮดโ€mediated autocrine release of death fa