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Regulation of Proliferation and Chondrogenic Differentiation of Human Mesenchymal Stem Cells by Laminin-5 (Laminin-332)

✍ Scribed by Junko Hashimoto; Yoshinobu Kariya; Kaoru Miyazaki

Book ID
111845569
Publisher
AlphaMed Press
Year
2006
Tongue
English
Weight
550 KB
Volume
24
Category
Article
ISSN
1066-5099

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## Abstract Human mesenchymal stem cell (hMSC) differentiation into osteoblasts and the signaling events involved are poorly understood. We recently established that contact with specific extracellular matrix (ECM) proteins, in particular laminin‐5, is sufficient to induce an osteogenic phenotype i