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Regulation of Proliferation and Apoptosis by Epidermal Growth Factor and Protein Kinase C in Human Ovarian Surface Epithelial Cells

✍ Scribed by Maryanne McClellan; Paul Kievit; Nelly Auersperg; Karin Rodland


Book ID
115603150
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
157 KB
Volume
246
Category
Article
ISSN
0014-4827

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## Abstract Epidermal growth factor (EGF), which stimulates tyrosine‐specific protein kinase activity both in vivo and in vitro, inhibits proliferation of A431 human epidermoid carcinoma cells. After mutagenesis clonal cell lines that were resistant to the growth inhibitory effects of EGF were sele