Regulation of pre-transfer RNA synthesis during transition from resting to growing state
β Scribed by Mauck, John C.; Green, Howard
- Book ID
- 122551867
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- English
- Weight
- 650 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0092-8674
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π SIMILAR VOLUMES
Thymidylate synthase (TS) activity is very low in resting mouse 3T6 fibroblasts but increases sharply in growth-stimulated cells at about the same time the cells enter S phase. To study the mechanism responsible for the increase in TS level, we isolated a 5-fluorodeoxyuridine (5-FdUrd)-resistant cel
## Abstract The rate of accumulation of dihydrofolate reductase (DHFR) was studied in resting, growing and serum stimulated mouse 3T6 fibroblasts by first exposing the cells briefly to 10^β6^ M methotrexate (MTX) to inactivate specifically and irreversibly the preβexisting enzyme, then determining