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Regulation of phospholipase D activity and ceramide production in daunorubicin-induced apoptosis in A-431 cells

โœ Scribed by Jun-Song Chen; Min-Qiang Chai; He-Hua Chen; Sheng Zhao; Jian-Guo Song

Book ID
117771963
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
649 KB
Volume
1488
Category
Article
ISSN
1388-1981

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We investigated the ceramide-induced apoptosis and potential mechanism in A-431 cells. Ceramide treatment causes the round up and the death of A-431 cells that is associated with p38 activation and can be observed in 10 h. Short-time ceramide treatment-induced cell death is not associated with the t