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Regulation of PDGF-stimulated SHIP2 tyrosine phosphorylation and association with Shc in 3T3-L1 preadipocytes

✍ Scribed by Y. Artemenko; A. Gagnon; S. Ibrahim; A. Sorisky

Book ID
118284266
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
373 KB
Volume
211
Category
Article
ISSN
0021-9541

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✍ Annemarie Gagnon; Yulia Artemenko; Thet Crapper; Alexander Sorisky πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 266 KB

## Abstract The role of the inositol lipid 5‐phosphatase (SHIP2) in preadipocyte signaling is not known. Although overexpression of SHIP2 inhibited proliferation and ^3^H‐thymidine incorporation in 3T3‐L1 preadipocytes, there was no effect on insulin‐induced adipogenesis. Insulin promoted SHIP2 tyr