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Regulation of nucleosomal core histone variant levels in differentiating murine erythroleukemia cells

✍ Scribed by Grove, Gregory W.; Zweidler, Alfred


Book ID
127077214
Publisher
American Chemical Society
Year
1984
Tongue
English
Weight
958 KB
Volume
23
Category
Article
ISSN
0006-2960

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## Abstract Notch signaling is a potential therapeutic target for various solid and hematopoietic malignancies. We have recently shown that downregulation of Notch‐1 expression has significant anti‐neoplastic activity in pre‐clinical models. However, the mechanisms through which Notch modulation ma