Certain human papillomaviruses (HPV), mainly types 16 and 18, have been widely recognized as an essential etiologic factor for the development of carcinoma of the uterine cervix. The early HPV proteins E6 and E7 are consistently expressed in the tumor cells, and cervical-carcinoma patients can devel
Regulation of nuclear receptor activities by two human papillomavirus type 18 oncoproteins, E6 and E7
โ Scribed by Wei-Ming Wang; Min-Huey Chung; Shih-Ming Huang
- Book ID
- 117053636
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 289 KB
- Volume
- 303
- Category
- Article
- ISSN
- 0006-291X
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Human papillomaviruses (HPVs) have been recognized as an essential pathogenic factor in anogenital cancer. HPV DNA has also been found in a subgroup of head-and-neck squamous-cell carcinomas (HNSCCs), and a causative role of the virus in the development of these tumors has been suggested by the conc
Human papillomavirus (HPV) DNA sequences are found in most carcinomas originating from the uterine cervix. HPV E6 and E7 oncogenes have been shown to cooperate with ras oncogenes to fully transform human epithelial cells. We investigated the effect of the Ha-ras oncogene on the transcriptional activ