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Regulation of nkx2.5 and mef2C by Hif-1alpha and Hdac9 during zebrafish cardiogenesis

✍ Scribed by Juan Ulloa; Ariel Reyes


Book ID
118505699
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
46 KB
Volume
356
Category
Article
ISSN
0012-1606

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Hypoxia inducible factor-1a (HIF-1a) stimulates expression of genes associated with angiogenesis and is associated with poor outcomes in ovarian and other cancers. In normoxia, HIF-1a is ubiquitinated and degraded through the E3 ubiquitin ligase, von Hippel-Lindau; however, little is known about the