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Regulation of Natural killer activity of lymphocytes from normal subjects and patients with chronic lymphatic leukemia by interaction between T and non-T cells

✍ Scribed by N. A. Khonina; G. Z. Shubinskii; V. P. Lozovoi


Publisher
Springer US
Year
1987
Tongue
English
Weight
271 KB
Volume
103
Category
Article
ISSN
0007-4888

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## Abstract To develop an effective antitumor immunotherapy for B‐lineage non‐Hodgkin's lymphoma, we constructed a tetravalent tandem diabody (tanDb) specific for both human CD19 (B‐cell marker) and CD3 (T‐cell antigen). Here, we report the effective killing of malignant primary B cells from patien