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Regulation of mouse Heparanase gene expression in T lymphocytes and tumor cells

✍ Scribed by de Mestre, Amanda M; Soe-Htwe, Thura; Sutcliffe, Elissa L; Rao, Sudha; Pagler, Eloisa B; Hornby, June R; Hulett, Mark D

Book ID
110041378
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
373 KB
Volume
85
Category
Article
ISSN
0818-9641

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## Abstract The tight skin 2 (Tsk2) mutation is an ENU induced dominant mutation localized on mouse chromosome 1. While the molecular defect is unknown, Tsk2/+ mice display cutaneous thickening associated with excessive matrix production and are used as a model of scleroderma. The purpose of this s