Leptin regulates MMP-2, TIMP-1 and colla
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Kristin Schram; Sabrina De Girolamo; Siham Madani; Diana Munoz; Farah Thong; Gar
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Article
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2010
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SP Versita
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English
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## Abstract A clear association between obesity and heart failure exists and a significant role for leptin, the product of the obese gene, has been suggested. One aspect of myocardial remodeling which characterizes heart failure is a disruption in the balance of extracellular matrix synthesis and d