Regulation of Mcl-1 by constitutive activation of NF-kappaB contributes to cell viability in human esophageal squamous cell carcinoma cells
β Scribed by Liu, Haidan; Yang, Jinfu; Yuan, Yunchang; Xia, Zhenkun; Chen, Mingjiu; Xie, Li; Ma, Xiaolong; Wang, Jian; Ouyang, Sufeng; Wu, Qin; Yu, Fenglei; Zhou, Xinmin; Yang, Yifeng; Cao, Ya; Hu, Jianguo; Yin, Bangliang
- Book ID
- 121543984
- Publisher
- BioMed Central
- Year
- 2014
- Tongue
- English
- Weight
- 767 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1471-2407
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We previously reported that human head and neck squamous cell carcinomas (HNSCCs) express the proinflammatory and pro-angiogenic cytokines interleukin (IL)-1a, IL-6, IL-8, and granulocyte-macrophage colonystimulating factor in vitro and in vivo. The promoter region of the genes encoding these cytoki
## Abstract Esophageal squamous cell carcinoma (ESCC) is an aggressive tumor with a poor prognosis. Although aberrant activation of Ξ²βcatenin/Tβcell factor (TCF) pathway has been observed in ESCC, mechanisms underlying this phenomenon remain unknown. Frequently rearranged in advanced Tβcell lymphom