𝔖 Bobbio Scriptorium
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Regulation of MAP kinases by docking domains

✍ Scribed by Hervé Enslen; Roger J. Davis


Book ID
114191795
Publisher
Portland Press
Year
2001
Tongue
English
Weight
168 KB
Volume
93
Category
Article
ISSN
0248-4900

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Transcriptional regulation by MAP kinase
✍ Roger J. Davis 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 951 KB

## Abstract Tyrosine kinase growth factor receptors activate MAP kinase by a complex mechanism involving the SH2/3 protein Grb2, the exchange protein Sos, and Ras. The GTP‐bound Ras protein binds to the Raf kinase and initiates a protein kinase cascade that leads to MAP kinase activation. Three MAP