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Regulation of MAP kinase-dependent apoptotic pathway: implication of reactive oxygen and nitrogen species

✍ Scribed by Vadim V. Sumbayev; Inna M. Yasinska

Book ID
116177310
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
449 KB
Volume
436
Category
Article
ISSN
0003-9861

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## Abstract This study addresses mechanisms by which interleukin‐1Ξ² (IL‐1Ξ²) regulates human chondrocyte apoptosis induced by a combination of the anti‐CD95 antibody CH‐11 and the proteasome inhibitor (PSI). The effect of IL‐1Ξ² on apoptosis varied among tissue samples. IL‐1Ξ² either enhanced (16/22 s