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Regulation of mammalian target of rapamycin and mitogen activated protein kinase pathways by BCR–ABL

✍ Scribed by Redig, Amanda J.; Vakana, Eliza; Platanias, Leonidas C.

Book ID
120946015
Publisher
Informa plc
Year
2011
Tongue
English
Weight
511 KB
Volume
52
Category
Article
ISSN
1042-8194

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## Abstract **Background:** The mammalian target of rapamycin (mTOR) regulates multiple cellular functions including translation in response to nutrients, especially amino acids. AMP‐activated protein kinase (AMPK) modulates metabolism in response to energy demand by responding to changes in AMP.