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Regulation of local availability of active tissue-type plasminogen activator in vivo in man

✍ Scribed by T. Hrafnkelsdottir; T. Gudnason; U. Wall; C. Jern; S. Jern

Book ID
109148574
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
222 KB
Volume
2
Category
Article
ISSN
1538-7933

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## Abstract Although originally known as a plasma serine protease involved in clot dissolution, tPA and its primary inhibitor, PAI‐1, play crucial roles in synaptic reorganization and plasticity in the central nervous system. In contrast to the wide array of work conducted in neural cells, relative