𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Regulation of LNS Domain Function by Alternative Splicing: The Structure of the Ligand-Binding Domain of Neurexin Iβ

✍ Scribed by Gabby Rudenko; Thai Nguyen; Yogarany Chelliah; Thomas C. Südhof; Johann Deisenhofer


Book ID
117267129
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
507 KB
Volume
99
Category
Article
ISSN
0092-8674

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Functional characterization of splicing
✍ Aitor Etxebarria; Lourdes Palacios; Marianne Stef; Diego Tejedor; Kepa B. Uribe; 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 569 KB

Familial hypercholesterolemia (FH) is an autosomal dominant disorder mostly caused by mutations in the LDLR gene. Although the detection of functional mutations in the LDLR gene provides an unequivocal diagnosis of the FH condition, there are many variants whose pathogenicity is still unknown. The a

Role of the αI domain in ligand binding
✍ Elaine M. Corps; Alexis Robertson; M. Joy Dauncey; Peter J. Kilshaw 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 350 KB

## Abstract The I domain of integrin αE was modeled on the crystal structure of that in CD11b and mutated to produce an open (high affinity) or closed (low affinity) conformation. K562 transfectants expressing mutant αE and wild‐type β7 were tested for adhesion to E‐cadherin‐Fc. Downward displaceme