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Regulation of left-right patterning in mice by growth/differentiation factor-1

โœ Scribed by Rankin, Christopher T.; Bunton, Tracie; Lawler, Ann M.; Lee, Se-Jin


Book ID
109827758
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
772 KB
Volume
24
Category
Article
ISSN
1061-4036

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## Abstract __Mahogunin Ring Finger 1__ (__Mgrn1__) encodes a RINGโ€containing protein with ubiquitin ligase activity that has been implicated in pigmentโ€type switching. In addition to having dark fur, mice lacking MGRN1 develop adultโ€onset spongy degeneration of the central nervous system and have