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Regulation of IRF2 transcriptional activity by its sumoylation

✍ Scribed by Ke-Jun Han; Ling Jiang; Hong-Bing Shu

Book ID
116296921
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
396 KB
Volume
372
Category
Article
ISSN
0006-291X

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## Abstract Small ubiquitin‐like modifiers (SUMO) are post‐translational modifiers that regulate target protein activity in diverse ways. The most common group of SUMO substrates is transcription factors, whose transcriptional activity can be altered positively or negatively as a result of SUMOylat