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Regulation of ion Permeation in the Selectivity Filter of Potassium Channels

โœ Scribed by Berneche, Simon; Wojtas-Niziurski, Wojciech; Heer, Florian

Book ID
122608906
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
42 KB
Volume
106
Category
Article
ISSN
0006-3495

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## Structure-function studies have shown that it is possible to convert a sodium channel to a calcium-selective channel by a single amino acid substitution in the selectivity filter locus. Ion permeation through the "model selectivity filter" was modeled with a reduced set of functional groups repr