The porcine kidney epithelial cell line LLC-PK, expresses a sodium-coupled glucose cotransporter (SGLTI) together with other differentiation markers of renal proximal tubule such as trehalase and y-glutamyltranspeptidase. Expression is regulated by cell density and exogenous differentiation inducers
Regulation of intracellular pH in LLC-PK1cells by Na+/H+exchange
โ Scribed by Marshall H. Montrose; Heini Murer
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 960 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0022-2631
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๐ SIMILAR VOLUMES
Several isoforms of Na / /H / exchanger (NHE-1-5) have been identified. LLC-PK1 clone 4 (CL4) expresses the amiloride-sensitive type of NHE predominantly in the basolateral membrane, which is believed to be NHE-1. It is not clear whether CL4 expresses NHE in the apical membrane and which side of NHE
Di-and tripeptides and peptide mimetics such as โค-lactam antibiotics are efficiently reabsorbed from the tubular lumen by a high-affinity peptide transporter. We have recently identified and characterized this H ฯฉ -coupled high-affinity peptide transport system in the porcine proximal tubular cell l