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Regulation of intracellular pH in cancer cell lines under normoxia and hypoxia

✍ Scribed by Hulikova, Alzbeta; Harris, Adrian L.; Vaughan-Jones, Richard D.; Swietach, Pawel


Book ID
118762717
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
510 KB
Volume
228
Category
Article
ISSN
0021-9541

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Tumor cells in vivo often exist in an ischemic microenvironment that would compromise the growth of normal cells. To minimize intracellular acidification under these conditions, these cells are thought to upregulate H Ο© transport mechanisms and/or slow the rate at which metabolic processes generate