𝔖 Bobbio Scriptorium
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Regulation of Intestinal Cholesterol Absorption

✍ Scribed by Wang, David Q.-H.

Book ID
118012655
Publisher
Annual Reviews
Year
2007
Tongue
English
Weight
276 KB
Volume
69
Category
Article
ISSN
0066-4278

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The ACAT2 gene encodes a gatekeeper of i
The ACAT2 gene encodes a gatekeeper of intestinal cholesterol absorption that regulates cholesterolemia and gallstone disease
✍ Silvana Zanlungo; Flavio Nervi πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 80 KB

The importance of cholesterol ester synthesis by acyl CoA: cholesterol acyltransferase (ACAT) enzymes in intestinal and hepatic cholesterol metabolism has been unclear. We now demonstrate that ACAT2 is the major ACAT in mouse small intestine and liver, and suggest that ACAT2 deficiency has profound