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Regulation of interleukin-1β–induced chemokine production and matrix metalloproteinase 2 activation by epigallocatechin-3-gallate in rheumatoid arthritis synovial fibroblasts

✍ Scribed by Salahuddin Ahmed; Angela Pakozdi; Alisa E. Koch


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
622 KB
Volume
54
Category
Article
ISSN
0004-3591

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## Abstract The purpose of this study was to investigate the possible involvement of synovium in cartilage destruction in osteoarthritis (OA) patients. Using human primary synovial fibroblasts (HPSFs), we examined the effects of glucosamine (GLN) on the regulation of the expression of matrix metall