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Regulation of Immune Activation/Retroviral Replication by CD8+ T Cells

✍ Scribed by JONATHAN D. POWELL; DANIEL P. BEDNARIK; TAMAR JEHUDA-COHEN; FRANCOIS VILLINGER; THOMAS M. FOLKS; A. A. ANSARI

Book ID
119866209
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
333 KB
Volume
636
Category
Article
ISSN
0890-6564

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πŸ“œ SIMILAR VOLUMES

Homeostatic regulation of CD8+ T cells b
Homeostatic regulation of CD8+ T cells by perforin
✍ David KΓ€gi; Bernhard Odermatt; Tak W. Mak πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 273 KB

To prevent uncontrolled expansion, the massive proliferation of T cells during an acute immune response has to be followed by controlled deletion. Here we show that similar to Fas, perforin is not only an important effector molecule of cytotoxic T lymphocytes (CTL) but also involved in down-regulati