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Regulation of IGF-I, IGFBP-4 and IGFBP-5 gene expression by loading in mouse skeletal muscle

โœ Scribed by Bonaventure Awede; Jean-Paul Thissen; Phillipe Gailly; Jean Lebacq


Book ID
117111703
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
277 KB
Volume
461
Category
Article
ISSN
0014-5793

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Osteogenic protein-1 (OP-1 or BMP-7) stimulates new bone formation in vivo and induces cell proliferation and differentiation of osteoblasts in vitro. Previous studies from our laboratory revealed that OP-1 led to a two-to threefold increase in steady-state insulin-like growth factor-I (IGF-I) and I