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Regulation of Id1 Protein Expression in Mouse Embryo Fibroblasts by the Type 1 Insulin-like Growth Factor Receptor

✍ Scribed by Barbara Belletti; Robert Drakas; Andrea Morrione; Xiao Tu; Marco Prisco; Tina Yuan; Ivan Casaburi; Renato Baserga


Book ID
115604299
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
445 KB
Volume
277
Category
Article
ISSN
0014-4827

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Nuclear translocation of insulin recepto
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## Abstract Translocation of the insulin receptor substrate‐1 (IRS‐1) to the nuclei has been reported to occur in cells stimulated by insulin‐like growth factor‐1 (IGF‐I) or expressing certain viral and cellular oncogenes. We show here that insulin can also induce nuclear translocation of IRS‐1 in