Regulation of hypoxic response elements on the expression of vascular endothelial growth factor gene transfected to rat skeletal myoblasts under hypoxic environment

Hypoxic response elements control expres

Hypoxic response elements control expression of human vascular endothelial growth factor165 genes transferred to ischemia myocardium in vivo and in vitro

✍ Bo Jiang; Hongyan Dong; Zhongming Zhang; Wei Wang; Yiqian Zhang; Xiahong Xu 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 406 KB

## Abstract ## Background Vascular endothelial growth factor (VEGF) gene transfer with recombinant adeno‐associated viral (rAAV) vector for ischemia heart disease therapy is being increasingly studied. However, uncontrolled long‐term expression of VEGF may cause some side effects. Therefore, an at