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Regulation of human profilaggrin promoter activity in cultured epithelial cells by retinoic acid and glucocorticoids

✍ Scribed by Presland, Richard B.; Tomic-Canic, Marjana; Lewis, S.Patrick; Dale, Beverly A.


Book ID
119560877
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
244 KB
Volume
27
Category
Article
ISSN
0923-1811

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## Abstract We previously demonstrated that 4‐oxoretinol (4‐oxo‐ROL) activated retinoic acid receptors (RARs) in F9 stem cells. We showed that 4‐oxo‐ROL inhibited the proliferation of normal human mammary epithelial cells (HMECs). To understand the mechanisms by which 4‐oxo‐ROL regulates HMEC growt