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Regulation of human globin gene expression in mouse erythroleukemia × human fibroblast hybrid cells

✍ Scribed by Devi Vembu; Neal S. Young; Marcia Willing; Eve Church; Linda Sanders-Haigh; W. French Anderson


Book ID
112558742
Publisher
Springer
Year
1982
Tongue
English
Weight
815 KB
Volume
8
Category
Article
ISSN
1572-9931

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We have stably transformed PCC4 and F9 teratocarcinoma stem cells with the human beta-globin gene. The transformed PCC4 cells retained their ability to produce in host mice tumours containing various differentiated tissues. Three of the five clones examined had human beta-globin transcripts, with co