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Regulation of HLA class II expression prevents allogeneic T-cell responses

โœ Scribed by Y. Jaimes; A. Seltsam; B. Eiz-Vesper; R. Blasczyk; C. Figueiredo


Book ID
110893285
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
672 KB
Volume
77
Category
Article
ISSN
0001-2815

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Signal transduction by HLA class II anti
โœ Niels ร˜dum; Paul J. Martin; Gary L. Schieven; John A. Hansen; Jeffrey A. Ledbett ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 805 KB

Human T cells express HLA class I1 antigens upon activation. Although activated, class II+ Tcells can present alloantigens under certain circumstances, the functional role of class I1 antigens on activated T cells remains largely unknown. Here, we report that cross-linking of HLA-DR molecules expres