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Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter

✍ Scribed by Lusic, M.

Book ID: 119770714
Publisher: Nature Publishing Group
Year: 2003
Tongue: English
Weight: 664 KB
Volume: 22
Category: Article
ISSN: 0261-4189
DOI: 10.1093/emboj/cdg631

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## Abstract We have addressed the correlation between sequence‐specific DNA binding by the tumor suppressor p53 and transactivation of various target genes, in the context of UV irradiation responses. In A549 cells (p53WT), p53 occupancy at the __p21__, __mdm2__, and __puma__ promoters increased si