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Regulation of Hemoglobin Synthesis in a Murine Erythroblastic Leukemic Cell: The Requirement for Replication to Induce Hemoglobin Synthesis

✍ Scribed by Patrick R. McClintock and John Papaconstantinou

Book ID
123652955
Publisher
National Academy of Sciences
Year
1974
Tongue
English
Weight
711 KB
Volume
71
Category
Article
ISSN
0027-8424

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✍ William Scher; Harvey D. Preisler; Charlotte Friend πŸ“‚ Article πŸ“… 1973 πŸ› John Wiley and Sons 🌐 English βš– 605 KB

## Abstract Erythroid differentiation of Friend leukemia cells is enhanced when the cells are grown for four days in the presence of dimethylsulfoxide (DMSO). Dimethylformamide (DMF) has a similar though less marked effect. 5‐Bromo‐2′‐deoxyuridine (BUdR) (10^βˆ’5^M) inhibits both DMF‐ and DMSO‐stimul