Regulation of Gremlin expression in the posterior limb bud
β Scribed by Sahar Nissim; Sean M. Hasso; John F. Fallon; Clifford J. Tabin
- Book ID
- 116976043
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 492 KB
- Volume
- 299
- Category
- Article
- ISSN
- 0012-1606
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## Abstract Multiple studies indicate that quantitative control of the levels of allβ__trans__βretinoic acid (RA) in the vertebrate embryo is necessary for correct development. The function of RA in cells is regulated by a number of coordinated mechanisms. One of those mechanisms involves controls
experiments i n question were carried out on embryos younger than stage 30. 1
The Gja1 gene encoding the gap junction connexin 43 (Cx43) is dynamically regulated during limb morphogenesis. Transcript expression is found in many regions of the limb bud known to be important in regulating limb growth and patterning. In the newly emerged limb bud, Gja1 transcripts are first expr