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Regulation of glutathione S-transferase gene expression by phenobarbital in cultured adult rat hepatocytes

✍ Scribed by Yves Vandenberghe; Lisa Tee; Fabrice Morel; Vera Rogiers; André Guillouzo; George Yeoh

Book ID
115925043
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
664 KB
Volume
284
Category
Article
ISSN
0014-5793

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Differential regulation of glutathione S
Differential regulation of glutathione S-transferases in cultured hepatocytes
✍ Mark Abramovitz; Seishi Ishigaki; Irving Listowsky 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 666 KB

Specific cDNA probes were used to determine steadystate mRNA levels for the multiple glutathione S-transferases in primary hepatocyte cultures. In the first 24 hr of culture, gene transcripts for the Y;, family decreased sharply, Yb3 disappeared completely, but changes in levels of mRNA for Y,,, and