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Regulation of genes for the cdc25 phosphatases is important for checkpoint control during the cell division cycle

✍ Scribed by Haugwitz, Ulrike; Wiedmann, Marcus; Spiesbach, Katja; Engeland, Kurt; Mossner, Joachim


Book ID
124124853
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
198 KB
Volume
120
Category
Article
ISSN
0016-5085

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## Abstract The serine/threonine kinase PAK4 regulates cytoskeletal architecture, and controls cell proliferation and survival. In most adult tissues PAK4 is expressed at low levels, but overexpression of PAK4 is associated with uncontrolled proliferation, inappropriate cell survival, and oncogenic