𝔖 Bobbio Scriptorium
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Regulation of gene expression by transfected subunits of cAMP-dependent protein kinase

✍ Scribed by Wolfgang BÜCHLER; Matthias MEINECKE; Trinad CHAKRABORTY; Tore JAHNSEN; Ulrich WALTER; Suzanne M. LOHMANN


Book ID
115127745
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
793 KB
Volume
188
Category
Article
ISSN
1432-1327

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## Abstract Ca^2+^ influx through L‐type voltage‐gated Ca^2+^ channels (L‐VSCC) is required for K^+^‐induced somatostatin (SS) mRNA. Increase in intracellular Ca^2+^ concentration leads to the activation of cyclic AMP‐responsive element binding protein (CREB), a key regulator of SS gene transcripti